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Aliyah
My name is Aliyah and I'm 19 and I am an acute myeloid leukemia survivor! Please watch my seven minute video of my journey: https://youtu.be/uxJs7N51BmQ Aliyah Petrone
Sadie
Diagnosed with leukemia at age 2, Sadie survived thanks to her remarkable treatment. A sunny and positive personality, Sadie today pursues her ambition as a dragster driver and is a living example of hope to other cancer patients.
Blastic Plasmacytoid Dendritic Cell Neoplasm
For personalized disease and treatment information, or to learn about clinical trials, contact one of The Leukemia & Lymphoma Society's (LLS's) Information Specialists at (800) 955-4572. BackgroundBlastic plasmacytoid dendritic cell neoplasm (BPDCN) was previously known as natural killer (NK) cell leukemia/lymphoma. As understanding of the biology and origin of this malignancy has improved, the World Health Organization (WHO) established the term blastic plasmacytoid dendritic cell neoplasm (BPDCN) in 2008.
Diagnosis
An accurate diagnosis of the type of leukemia is important. The exact diagnosis helps the doctor to estimate how the disease will progress and determine the appropriate treatment
Diagnosing acute myeloid leukemia (AML) and your AML subtype usually involves a series of tests. Some of these tests may be repeated during and after therapy to measure the effects of treatment.
Diagnosis
Diagnosing juvenile myelomonocytic leukemia (JMML) usually involves ruling out other similar diseases such as chronic myelomonocytic leukemia and chronic myeloid leukemia, especially if your child is older than 6 years. Doctors commonly use blood tests and bone marrow tests to diagnose JMML.
The tests used to diagnose JMML include:
Janet
I was diagnosed with acute myeloid leukemia (AML) at the age of 28, and our firstborn son was four months old. I am currently a 36-year survivor, married 41 years with four sons, four daughters-in-law, and eight grandchildren.
CMML Subtypes
Most people diagnosed with chronic myelomonocytic leukemia (CMML) have one of three different subtypes of CMML. Doctors classify CMML subtypes by the percentage of blast cells ("blasts") in the blood and bone marrow.
Doctors use a classification system developed by the World Health Organization (WHO) in 2001 and updated in 2016. The three subtypes are:
Chemotherapy and Drug Therapy
If you're being treated for chronic myelomonocytic leukemia (CMML), your first line of defense may be drug therapy. You'll be given potent drugs that must be toxic enough to damage or kill the cancer cells. At the same time, these drugs take aim at normal cells and cause side effects. Yet, not everyone experiences side effects and people react differently.
Drugs Used for CMMLThere is no one standard treatment for CMML. There are three FDA approved treatments for patients, which include:
Sandra
I'm a survivor of multiple myeloma and MDS. Now I just want to raise awareness for the cause its seriousness.
Having both these diseases is tough, but I'm trying to take it all in and The Leukemia & Lymphoma Society offers wonderful support.
Facts and Statistics Overview
Leukemia, lymphoma, myeloma, myelodysplastic syndromes (MDS), and myeloproliferative neoplasms (MPNs) are types of cancer that can affect the bone marrow, the blood cells, the lymph nodes, and other parts of the lymphatic system.
Click on the links below to view statistics about each disease:
Lindsay
Hello, my name is Lindsay. I was recently diagnosed with chronic myeloid leukemia (CML).
Among being diagnosed with this my husband and I have been going through infertility as well. It is helpful to connect with others going through the same process that we are.
God bless!
Relapsed and Refractory
Some patients have residual leukemia cells in their bone marrow even after they receive intensive treatment. In these cases, the disease is referred to as being “refractory” (or “refractory ALL”).
Other patients achieve remission but later have decreased numbers of normal blood cells and a return of leukemia cells in their bone marrow. This is referred to as a “relapse” of the disease (or “relapsed ALL”).
Tracy
In 2001 at the age of 31, I was living in Maui working at the Ritz Carlton and began to feel sick. I had a rash on my hand, was tired, losing weight, and just did not feel well. I had been healthy all my life so thought it would pass.
Marty
My story is very unique. Christine and I got married in July of 1979. In August she was diagnosed with acute lymphoblastic leukemia (ALL). As we all now know, the prognosis at that time was not the best for an adult with ALL. There was a new procedure called a bone marrow transplant. Chris was not a candidate and seven months after we were married, she passed away at the age of 26.
Amos
Amos is 6 years old and has been in treatment for leukemia since September 2017.
Three weeks after his very first day of kindergarten, he was diagnosed with Acute Lymphoblastic Leukemia (ALL). Amos spent a month in the hospital for the initial induction phase of his treatment, and then was homebound for 9 more months while he continued his intensive chemotherapy regimen. His immune system was so compromised that he could not attend school or be in public spaces. He received tutoring from a teacher twice a week at home.
Helena
In 2018, a few days before Thanksgiving, Helena noticed something. She was having difficulty lifting speakers at her gigs. She became winded after only a few songs. Even the most minute tasks became daunting.
Jaiden
My son, Jaiden was diagnosed with T-cell acute lymphoblastic leukemia (ALL) on November 21, 2018. Prior to his diagnosis, Jaiden was a very well-rounded athlete and he played almost every sport, until one day during a football he fractured his arm and was done for the season. Needless to say, he was in a cast for 6 weeks.
Terry
My life has been an interesting journey. In April 2019, I lost my wife of 20 years, and in August 2020, I lost my older brother to leukemia. My wife was 50, and my brother was 64. After several months of excruciating pain in my abdomen, I was finally diagnosed with non-Hodgkin B-cell lymphoma (B-NHL) in May 2021. I was 58. Upon entering the hospital in June for my first round of chemo, I was diagnosed with acute renal failure. After several days of treatment, I finally started my chemotherapy. I was lucky, or so I thought, no radiation for me.
Lauren
In the fall of 2022, my cousin lost her battle with leukemia. She was the most lovely (a word that makes me think of her) and kind person, and at the memorial service, Kate's sister said Kate had said, "There is nothing better than to be young and to run." This sentiment stuck with me for a long time as I am also a runner, and I started thinking about how I could honor her in my own way. The family had directed those who wished to donate to The Leukemia & Lymphoma Society (LLS), so I researched and discovered Team In Training (TNT).
Signs and Symptoms
Signs and symptoms vary from patient to patient and depend on the type of CMML. Click here to learn more about subtypes of CMML.
Those with a myelodysplastic subtype (MD-CMML) tend to present with low blood cell counts. Signs and symptoms may include:
Sahara
In August 2021, I was diagnosed with stage IV Hodgkin lymphoma (HL). I am now cancer-free. The Leukemia & Lymphoma Society (LLS) helped me tremendously throughout my process. I had the privilege of raising money for LLS through an Instagram campaign by sharing my story online.
Chemotherapy
Because of acute lymphoblastic leukemia's (ALL's) rapid growth, most patients need to start chemotherapy soon after diagnosis.
Chemotherapy drugs kill fast-growing cells throughout the body including cancer cells and normal, healthy cells. The damage to normal, healthy cells can cause side effects. Yet, not everyone experiences side effects the same way.
ALL treatment consists of: