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Radiation Therapy

Radiation therapy, also known as “radiotherapy,” uses high-energy x-rays or other types of radiation to kill cancer cells in a small, targeted area of the body. Since radiation can also harm normal cells, whenever possible, radiation therapy is directed only at the affected lymph node areas in order to reduce the long-term side effects.

Signs and Symptoms

MF usually develops slowly. MF often does not cause early symptoms and may be found during a routine blood test. When fibrosis develops in the bone marrow, the bone marrow is unable to produce enough normal blood cells. The lack of blood cells causes many of the signs and symptoms of MF. These include:

Signs and Symptoms

Polycythemia vera (PV) develops slowly, and it may not cause symptoms for many years. The condition is often diagnosed during a routine blood test before severe symptoms occur. 

Symptoms may include:

MDS Subtypes

There are several kinds (subtypes) of MDS. The subtype is determined from the results of the blood and bone marrow tests.

WHO Classification

The current WHO classification guidelines identify six subtypes.The current WHO classification guidelines, which were updated in 2022, groups MDS based on genetic abnormalities and morphologically defined features (the appearance and number of the cells under a microscope).

The subtypes are determined by the following:

Chemotherapy and Drug Therapy

Chemotherapy is the mainstay of treatment for HL. A combination chemotherapy regimen consists of two or more chemotherapy drugs. Generally, the drugs are dissolved in fluid and usually administered via a peripheral intravenous (IV) line. If finding an accessible vein is problematic, a central line (a port, or a peripherally inserted central venous catheter (a PICC or PIC line) may be used for some HL patients. 

Disease Complications

Myeloma and treatment of myeloma can lead to mild to serious health complications and side effects. Some of these symptoms can be managed with ongoing supportive (palliative) care. Others may be medical emergencies requiring immediate attention. Always tell your healthcare team if you experience new or worsening symptoms. 

Pain

Pain related to myeloma or myeloma treatment can include 

Related Diseases

Myeloma shares some similar features and symptoms with other blood disorders, including:

Vonshel

Vonshel

Hi, my name is Von, and back in 2008, I was diagnosed with breast cancer. I didn't want to die, but prayer and God sent me right to the perfect doctor: Dr. Moran from Brunswick, GA. I got through chemotherapy and radiation with a breeze, and I'm now in remission for 13 years.

JE

Jacqueline

It’s been five years since my daughter was diagnosed with stage ¾ Hodgkin lymphoma (HL). She had just graduated college, and she had a lump on her right clavicle area. We went to the doctor, and then it all started, from CT scans to biopsy to telling us that it would be six months of chemo, and that’s it.

erica

Erica

Erica was diagnosed with potentially fatal Stage 4 Hodgkin Lymphoma on March 28, 2013. Her journey to survive her battle with cancer was very trying but after overcoming her obstacles, Erica is very passionate about inspiring people to have the d’zire to survive any challenges that they may face in their lives. Erica’s fight to survive lymphoma had its highs and its lows, however, she didn’t give up even when at times her battle seemed like it wasn’t getting any easier.

sherry

Sherry

Last March, my husband Bruce went in for what was supposed to be a "simple" surgery. When the doctor opened him up, she found a mass the size of a honeydew melon (her description to me) wound around his intestines and colon. She essentially did cancer surgery on the spot and removed lymph nodes and the tumor.

Jack

Jack

Jack is a particularly big fan of the Leukemia & Lymphoma Society.  His is an active Patient Advocate managing a local support group for patients and caregivers interested in his rare blood cancer, he participates in LLS' First Connection program, has helped with LLS' Team in Training and Light the Night recruiting efforts.  He received LLS' appreciation award "For Outstanding Commitment and Support of Advocacy and Patient Quality of Life" in June 2104.

Maria

Maria

By the end of November 2008, I started feeling an overwhelming fatigue. I developed a fever and my physician sent me urgently to the emergency room. There I was found to be depleted of blood and needed a transfusion. It seemed so unreal.

After a couple of days and a bone marrow biopsy, I was diagnosed with acute myeloid leukemia (AML). I learned that if I had not sought help in the ER, I could had died.

Jesse

Jesse

My name is Jesse Jordan. I'm a 37 year cancer survivor. I was diagnosed with acute lymphocytic leukemia (ALL) when I was 17 months old. Cancer has been one of the defining moments of my life and it helps me keep the right perspective towards life. The moment I take life for granted, cancer reminds me of how precious life is and how blessed I am to be here. I believe I am meant to share my cancer story with others. Cancer increases my awareness of life every day and reinforces my commitment to help others. My hope is that my personal cancer story can give hope to others.

Mark

Mark

On October 16, 2015, my dad was diagnosed with acute myeloid leukemia (AML). I remember the day as if it was yesterday. It is so crippling. Right away, my dad transferred to OHSU to start treatment with my mom by his side. With three rounds of chemo and a bone marrow transplant on the calendar, my dad's days came to an end on February 3, 2016. This strong, funny, humble, and loving man that is my dad is gone.

Lenny

Lenny

I am nominating an extraordinary person, that I have never met in person before.  This person truly changed my life in many ways.   He has performed many positive actions that changed my perspective and outlook of people for the better. He truly has the power to change millions of people's and or their family's lives, and my family and I were fortunate to be the recipients of access to his extensive knowledge base and his immediate comforting support.  

Tricia Plasma cell leukemia

Trisha

In November 2019, Trisha and her husband were thrilled to have given birth to her second daughter. At this time, she went to visit her OBGYN for her 6-Week Postpartum Exam, and to her surprise, her doctor noticed she had an enlarged spleen and liver. She was immediately instructed to go to the emergency room, where she was admitted for one week. After a bone marrow biopsy, Trisha was diagnosed with plasma cell leukemia (PCL). Three days later, I went to another follow-up with my oncologist.

lymphoma LTN

Brooke

In September 2014, just shy of four months after college graduation, I was blindsided sitting in the emergency room at Duke Hospital.

acute lymphoblastic leukemia (ALL)

Martha

I want to share the story of how my mom, who has acute lymphocytic leukemia (ALL) inspired me to fight for my dreams, overcome every obstacle, and create a new beauty brand.

acute lymphocytic leukemia (ALL)

Martin

On February 15, 1993, seven-year-old Martin was diagnosed with acute lymphocytic leukemia (ALL). During the following three years, Martin, like so many other young cancer patients, experienced a series of painful procedures, as well as intensive chemotherapy as part of his treatment protocol.

stage 4 Hodgkin lymphoma (HL)

Lisa

On February 3, 2020, my life changed forever. My husband and I welcomed our first child, a baby girl named Quinn. But, three weeks after she was born, I started to not feel the best.

On Friday, March 13, 2020, the day of the COVID-19 shutdown, my life changed forever again. After two weeks of having fevers and night sweats and being tested for everything but cancer, I went in for scans. Two hours after I had my scans, I got the call that nobody wanted to hear. I had cancer.