Skip to main content

Search Results

A Special Delivery for Mom with Cancer

On April 8, 2016, I was diagnosed with acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML). I was 23 weeks pregnant. For almost five years, my husband, Allan, and I battled unexplained infertility. After three failed fertility treatments, we finally found ourselves pregnant the “au natural” way!

Understanding Mutations to Treat MDS

Benjamin Ebert is researching what genetic mutations cause myelodysplastic syndromes (MDS), a group of disorders in which the bone marrow fails to produce sufficient blood cells, and how that information can be used to determine prognosis and therapy. MDS frequently progresses to an acute leukemia.

researcher

What’s Next in Blood Cancer: Looking Ahead to 2023

The most important blood cancer scientific meeting, the American Society of Hematology (ASH), is held every December.

Cancer Won’t Stop Coach Marie

Thousands of runners will hit the streets of Chicago this weekend for the 2016 Chicago Marathon. Before they cross the start and finish lines, they will go through an intense training program to meet one of their most challenging goals: 26.2 miles.

As a coach for The Leukemia & Lymphoma Society’s Team In Training (TNT), Marie Jarrell of Chicago is the inspiring drumbeat for hundreds of Chicago marathon trainees every year, leading them down the path to fitness and providing them with inspiration along the way.

Walgreens gift certificate recipients in front of balloons in Bakersfield

Finding Support in Community: Walgreens and LLS Show Up for Blood Cancer Patients

We all need a helping hand sometimes.  

Add on a cancer diagnosis and the everyday suddenly feels... different. In many ways, harder. 

Interferon alfa-2a

Interferons are substances naturally produced by cells in the body to help fight infections and tumors. They may also be synthetic versions of these substances. Interferon alfa-2a is FDA approved to treat people who have hairy cell leukemia and Philadelphia chromosome positive chronic myeloid leukemia who are minimally pretreated (within 1 year of diagnosis). It may cause a temporary loss of hair. After treatment has ended, normal hair growth should return.


 

Ibrutinib

Ibrutinib has been FDA-approved to treat:

  • Patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).
  • Patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (SLL) with 17p deletion.
  • Patients with Waldenström macroglobulinemia (WM).
  • Adult and pediatric patients age 1 year and older with chronic graft versus host disease (cGVHD) after failure of one or more lines of systemic therapy.

Rituximab

is FDA approved for the treatment of:

Stopping Gleevec to Start a Family

Erin Zammett Ruddy is a magazine journalist and blogger who was diagnosed with chronic myeloid leukemia at age 23. Today, she is a 40-year-old mother of three. 

On January 30 I turned 40. The big 4-0! My grandma Adele and I shared a birthday, and she’d be aghast if she knew I was telling all of you my real age right now. Grandma Del was a Radio City Rockette and very glamorous—and she never turned a day over 29, despite living to 85 (sorry, Grandma). But I am damn proud of being 40, newly-formed wrinkles and all.

#ASH18: Update on Immunotherapy

Immunotherapy – harnessing the body’s immune system to fight disease – is rapidly becoming a mainstay of cancer treatment. The increasing interest in this field was clear at yesterday’s standing-room only symposium hosted by The Leukemia & Lymphoma Society in advance of the 60th ASH (American Society of Hematology) Meeting which officially kicks off today here in San Diego. Over the next few days more than 30,000 researchers and others connected to the blood cancers and other blood malignancies will gather to hear the latest data from clinical trials.

Charting the surfaceome to eliminate hairy cell leukemia (HCL)

To optimize treatment of HCL, we dissect the tumors` surface proteome to understand a) surface mediated signals and b) the dependence on BRAFV600E activity, to c) eradicate remaining cell populations after BRAF inhibitor treatment. We use chemoproteomics, which enable mass-spectrometric-based surfaceome discovery to quantitatively investigate HCL. We expect to identify HCL specific and BRAF-dependent surfaceomes and identify new and critical targets for treatment.

Niclosamide for the treatment of relapsed pediatric acute myeloid leukemia

Niclosamide is an FDA approved anti-parasitic drug that is well tolerated in adults and children. AML cells are sensitive to niclosamide, act synergistically with chemotherapy in vitro, and inhibit the proliferation of primary AML stem cells in vivo. We propose to examine the effects of niclosamide in combination with chemotherapy in animal models of AML and study the mechanism of action of niclosamide in AML cells in anticipation of a clinical trial in children with relapsed AML.