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Chemotherapy and Drug Therapy
Chemotherapy is the mainstay of treatment for HL. A combination chemotherapy regimen consists of two or more chemotherapy drugs. Generally, the drugs are dissolved in fluid and usually administered via a peripheral intravenous (IV) line. If finding an accessible vein is problematic, a central line (a port, or a peripherally inserted central venous catheter (a PICC or PIC line) may be used for some HL patients.
Disease Complications
Myeloma and treatment of myeloma can lead to mild to serious health complications and side effects. Some of these symptoms can be managed with ongoing supportive (palliative) care. Others may be medical emergencies requiring immediate attention. Always tell your healthcare team if you experience new or worsening symptoms.
PainPain related to myeloma or myeloma treatment can include
Related Diseases
Myeloma shares some similar features and symptoms with other blood disorders, including:
Follow-Up Care
Follow-up care is important with both aggressive and indolent forms of NHL because if the disease recurs, curative options are still available for many people. Follow-up care needs to be individualized and should be based on several factors, including how the disease initially manifested. Patients who are in remission should continue to be monitored by clinical assessment as determined by their doctor. In the past, computed tomography (CT) scans or other diagnostic imaging were done routinely in an attempt to detect relapse.
Relapsed and Refractory
Most patients with classical HL are cured by their initial (first-line) treatment. However, in a significant percentage of patients—especially those with advanced stage HL—the disease relapses or is refractory.
- Relapse means the disease comes back after a remission following treatment.
- Refractory means the disease has not responded to treatment.
For these patients, HL is still potentially curable.
Side Effects
The main goal of treatment for myeloma is to get rid of myeloma cells. The term side effect is used to describe how treatment affects healthy cells. Patients react to treatments in different ways. Sometimes there are very mild side effects. Other side effects may be serious and last a long time.
Myeloma patients should talk with their doctors about side effects before they begin any type of treatment. There are drugs and other therapies can prevent or manage many side effects.
Prognostic Factors
Prognosis is the likely outcome of a disease along with the chance of recovery or recurrence. Hodgkin lymphoma (HL) cases are generally classified into the three subgroups described below.
Jonathan
I’ll start from the beginning.
In 2012, I was diagnosed with testicular cancer. I had surgery to remove the mixed germ cell tumor and then was on the road to recovery. My lymph nodes were larger than they should have been, so I opted to err on the side of caution and had a lymph node dissection to have them removed. That was an invasive surgery that kept me out of work and from doing any physical activity for over six months. Once I healed up, I went back to work as a full-time police officer in Worcester, MA.
Kimberly
In October of 2020, I became sick with a sinus infection. After a 10-day dose of antibiotics, I was still sick, and the doctor gave me a stronger dose of antibiotics. Once I finished the five-day dose, I felt better, but every day I had a headache. After 28 days of continuous headaches, I decided to call the doctor again and let him know. It was a Friday, and he was off, so I was told to wait until the following Monday. Over the course of the weekend, I developed another sinus infection and lesions on my body, including on my uvula.
NHL Subtypes
More than 60 specific NHL subtypes have been identified and assigned names by the World Health Organization (WHO). NHL subtypes are categorized by the characteristics of the lymphoma cells, including their appearance, the presence of proteins on the surface of the cells and their genetic features. It's important to know your subtype since it plays a large part in determining the type of treatment you'll receive. A hematopathologist, a doctor who specializes in the diagnosis of blood disorders and blood cancers, should review your biopsy specimens.
Coping With Cancer
When someone is diagnosed with cancer, everyone in his or her family is affected. This holds especially true when a child has cancer. Different families have different ways of coping, but there are some sound strategies that anyone can employ. For useful tools and tips that may help, see the following pages:
Jason
From an early age, Jason Wexler showed an interest in curing cancer and would even make "potions," according to his mother, Sherri. An extrovert like his father, Kevin, Jason has always liked making a difference for others and has great ideas to share.
When he turned sixteen, the sophomore at The Grauer School in Encinitas knew he wanted to do something to help give back. Jason learned about the "Students of the Year" program for The Leukemia & Lymphoma Society (LLS) and knew he had to get involved.
Amrita
November 2007 was the start of my journey as a cancer warrior and survivor. I was diagnosed with Diffused Large B cell non-Hodgkins lymphoma (NHL) and it is incredible for me to reflect on the fact that I am coming up on my 15th year anniversary of diagnosis and treatment. I do hear and read powerful stories of other survivors and in so many ways I think my journey with and after cancer diagnosis resonates with those.
Oya
My three kids are my precious jewels, the reason I get up every morning. As a single parent, providing a good life for them is what fuels my drive to succeed. Little did I know that need to care for them would end up saving my life.
Chase Malone
I am a Hodgkin’s lymphoma survivor. It took me seven months to build up the courage to share my story, but if my story inspires even just one other patient like myself, I’d be more than grateful.
I was 21 and had just graduated a year early from Florida State University with my finance degree. I moved to Miami to start my dream career in commercial real estate investment finance. I was seemingly on top of the world before tragedy struck.
Bryon
In 2017, during a pickup basketball game at the local gym, Bryon Daily was beginning to feel his age, playing against 20-year-olds. A former college track athlete in his early 50s, this fatigue felt different. He also fractured his finger during a routine pass in the game. Bryon’s primary doctor at Kaiser ordered labs including blood and urine, that showed impairment in his protein levels and referred him to a urologist then a hematologist.
Mya
In 2017, Mya was just two years old when diagnosed with acute myeloid leukemia (AML M6) in her central nervous system, which created solid tumors in her brain and spine.
Mya started having seizures in February 2017, after hitting the back of her head on a sliding board in our yard while playing with her big brother, Logan. After a few more seizures which led to several emergency room visits, an EEG was scheduled as well as an MRI.
Nicolas
My name is Nicolas and I am 14 years old. Before my diagnosis I was a completely healthy child, in fact I was rarely ever sick. I played baseball, had straight A’s, and recently had recently got a new puppy. This sense of normalcy came to a screeching halt on January 13, 2018. That’s the day I was admitted into the pediatric ICU and the day I first heard the words, “you have cancer.” My family and I were devastated.
Gezell
Calvin and I are the best of friends, playmates, and hopeless romantics! We found each other in midlife, and we’ve decided to remain newlyweds because we can! We have the privilege of working together every day, and we really love it! Christ is the foundation for our marriage, so the adversities we have faced together made our relationship strong and stable.
Kiana
In July 2013, during what was supposed to be a normal sports physical, I turned my head to the side to talk to my doctor, and my mom noticed something, "Is that a lump on her throat?" she asked. An ultrasound and biopsy afterward revealed that I had papillary thyroid carcinoma, a type of thyroid cancer that required major surgery to remove my thyroid and a few affected lymph nodes from my neck, along with radiation treatment. Though they caught it early and I didn't need chemotherapy to treat my cancer, the treatment was still very difficult for me to deal with.