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Pan-heme CAR: Anti-CD38 CAR T cells for myeloid, lymphoid and plasma cell malignancies
Our SCOR team has a razor-sharp focus on an exciting new treatment modality for blood cancers: chimeric antigen receptor (CAR) T cells. T cells can be trained to target cancer cells by genetic modification. In fact, previous support from the Leukemia & Lymphoma Society allowed us to successfully develop CAR T cells targeted to CD19, a pan-B cell marker.
Volunteers: The Engine Powering LLS’s Mission
I was always aware that volunteers with The Leukemia & Lymphoma Society (LLS) drive impact for blood cancer patients and families. But it wasn’t until Thanksgiving Day 2007 that I discovered the full force of their power. My wife, Holly, had recently been diagnosed with follicular lymphoma and our family was still reeling from the news. She was feeling quite ill, and we were exhausted with worry and trying to keep life as normal as possible for our two young children.
Defining and Redefining a Blood Cancer Diagnosis
Science historian June Goodfield wrote, “Cancer begins and ends with people.”
This Blood Cancer Awareness Month, it’s important to know that The Leukemia & Lymphoma Society (LLS) is on a mission to cure blood cancers and improve quality of life for the nearly 1.7 million people in the U.S. living with or in remission from blood cancer.
LLS is all about people—an organization full of people who are united in the urgent effort to help every person impacted by blood cancer.
Exercise for blood cancer patients
Table of contents:
Georgia
Today I would like to give thanks to The Leukemia & Lymphoma Society. With the fantastic staff, and volunteers we have truly come so far. As an ALL survivor, Team In Training Alumni, and participant it is so amazing to see what we have all done for blood cancer patients and their families.
Alexis
CANCER, that one word that sits like a lump in the back of your throat making you unable to swallow...
I was in sixth grade when my hero, my dad, was diagnosed with hairy cell leukemia.
Over the years, my dad has gone through his fair share of chemotherapy. Usually after treatment, his cancer became dormant, and then resurfaced a few years later. The dreadful "process" would repeat itself, getting a little harder each time as his body became resistant to the therapy.
Alison & Keith
This is a love story about two Team In Training honorees, Alison and Keith. Keith has been a recreational runner for many years and first learned of Team In Training (TNT) as a fundraising sponsor for a friend. Upon his diagnosis of follicular lymphoma in 2008, Keith says he knew right away that direct involvement with TNT was an obvious step; he became an honoree for the South Bay and Peninsula run teams during his initial chemotherapy treatments, and ran with the teams every few weeks in that first “honoree season.”
Johanna
I am a teacher from Texas. My journey to Team and Training wasn’t immediate. I moved to Texas from Louisiana. When I moved to Texas, I decided to start running to meet people and to help with my homesickness.
Chris
When I started this journey six years ago, I never would have imagined I would take part in TEN Team In Training events, but losing a great friend can motivate you to do incredible things.
Rachel
Rachel was diagnosed with stage 4B Hodgkin lymphoma in February 2015. She was 26 years old. The moment when her oncologist first spoke the words “you have cancer” were surreal to her. She looked to her parents who exchanged the same look of disbelief and shock, then quickly looked away before fear and sadness settled across their faces. Her mind started to race, “How am I stage 4? I don’t feel that sick. This has to be a mistake, where did this even come from? What happens now?”
Lynette
It all started with a race... I began running back in 2011 with the sole purpose of losing weight. I joined a running group and became interested in races, specifically the Nike Women's Half Marathon.
Kathie & Dave
Dave and I have been a part of The Leukemia & Lymphoma Society (LLS) since 1998. I can’t even remember how many Team In Training events we’ve done. We have both done at least one a year if not more since Michael, our son, was diagnosed.
This picture explains it all. Michael was 5 years old when he was diagnosed and of about 10 kids going through treatment with him at the time, I think only he and another are still here today. I know the statistics should be better but that’s the reality for us.
Volunteer
It all began in 2010 after my friend Cara and I ran the LA Marathon. We had already trained on our own for the 26.2 miles race. I thought, “Why not just keep running?” That’s when I found the nonprofit The Leukemia & Lymphoma Society and their fundraising program called Team In Training (TNT)! TNT was the only program you could volunteer with to get a secured race entry into the San Francisco Nike Women's Marathon. So, I registered for an informational meeting at the mall near my parents' house, listened to the staff and coaches, as well as a survivor, and I was hooked.
Jaimie Potvin
Finding cures for cancer is especially close to my heart. In 2011, my brother, Cory was diagnosed with large B-cell lymphoma. Our dad was already a two-time survivor of non-Hodgkin lymphoma, so we truly believed he would survive blood cancer too. When his treatment showed no signs of improvement, it was devastating. Cory died six years ago and I still miss him so much every single day.
Boyd
Greetings from a friend in Canada! I am a two-time blood cancer survivor and marathon runner all because of the love of friends in The Leukemia & Lymphoma Society (LLS)! I had a life saving stem cell transplant from an American Naval Serviceman named Nathan Barnes who was in Japan when he saved my life. (2011-12). My stem cell transplant was May 2012!! A year after my stem cell transplant a friend took me to Alaska and ran a marathon for me with Team in Training! (2013).
Nicolasa
The first time I heard of Team In Training (TNT) and raising money for The Leukemia & Lymphoma Society (LLS) was when my friend and I wanted to run the Nike Women's Half in D.C. We filled out the application and got accepted and started raising money, not having a clue about where this path was going to lead us. It was at that time that I began to realize the impact leukemia and lymphoma have had on my family and friends, whether they or a loved one had gone through treatment. I wrote all of their names on my singlet and carried them with me along that course.
Sandy
In the summer of 2006 I received a letter in the mail much like what you get around the holidays telling of the adventures over the past year. My friend had recently moved to Tucson with her family. She shared pictures of their kids and told about the transition from the Seattle area to Tucson.
Katie
Twenty years ago I did two things that shaped my life.
Jeannine
I got started with The Leukemia and Lymphoma Society (LLS) when our good friend, Tim Mauro, ran for Man of the Year and my husband, Larry, was his “campaign manager.” Tim’s father-in law, Bob, was battling non Hodgkin lymphoma. Watching them battle with him and seeing everything they did to help was such an inspiration, and seeing how many people were bonded together, raising money to find a cure, was amazing.
Cassie
Cassie Fetsch is a regular volunteer for The Leukemia & Lymphoma Society’s (LLS) Minnesota chapter. When school is out, staff members can count on Cassie to be in the office folding letters, stuffing and labeling envelopes, counting Team In Training brochures, cleaning out drawers or putting together pizza boxes. Since Domino's sponsors LLS's Pennies for Patients program, they donate all the boxes to ship campaign supplies. This year, Cassie assembled boxes for more than 800 schools!
Types of Complementary Therapies
An integrative healthcare team evaluates the physical, emotional and spiritual needs of each patient and then recommends specific therapies and lifestyle changes as part of a comprehensive treatment plan. Team members consider the scientific evidence, identify risks and benefits, and take into account individual preferences when they advise patients about complementary therapies.
Ron
This started 11 years ago when my mom was first diagnosed with lymphoma. I wanted to do more and saw the purple team always out running events I was entered into. I wanted to join and did in 2010. I have run in countless events over the years with Team In Training (TNT). Then my mom passed in May of 2017 while I was training for the Walt Disney World event. I was crushed and continued to run in her honor. My mom was supposed to be at the finish line at my 2018 Walt Disney World Marathon Weekend, and it did not happen.
Heather
The world works in mysterious ways, it truly does! When I first volunteered with The Leukemia & Lymphoma Society's (LLS) Team In Training (TNT) program in 2015, I never in a million years thought I would be fundraising in honor of my husband Dave. I started out fundraising for my step-grandmother Margaret and his grandmother Pearl. Eventually, the list of people I ran and fundraised in honor or memory of grew to way over 20! All that time it turns out I was fundraising for Dave, too, we just didn't know it yet!