Search Results

A phase 2 study of RVU120, a novel CDK8 inhibitor, in genetically defined cohorts of patients with AML and high-risk MDS

In August 2017, LLS TAP partnered with Ryvu Therapeutics (formerly known as Selvita) to support "A Phase 1b Study of SEL120 in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome." Ryvu Therapeutics is a clinical-stage drug discovery and development company focusing on novel small molecule therapies that address emerging targets in oncology using a proprietary discovery engine platform.

A phase 2 study of RVU120, a novel CDK8 inhibitor, in combination with venetoclax in patients with AML

A phase 2 study of RVU120, a novel CDK8 inhibitor, in patients with low-risk MDS

A phase 2 study of RVU120, a novel CDK8 inhibitor, in patients with myelofibrosis

Financial and Legal

Balancing Work

The many responsibilities of caring for someone often leads to job conflicts. Work is a financial necessity and a major source of personal satisfaction, but for many caregivers, it is often difficult to balance the twin responsibilities of caregiving and working. Each caregiver’s working conditions are different. Talk to your supervisor and look in the employee handbook or other human resources publications to learn about your company’s policy on caregivers.

Epigenetic Mechanisms and Targeting in Hematological Malignancy

Blood cancers can be caused by aberrant regulation of genes that control cell growth and development. The root cause of this problem may be the presence of mutant regulator proteins in the cell and abnormal switching on or off of target genes. Our SCOR studies the molecular basis of this gene deregulation using cell cultured in the laboratory, in human specimen and animal models.

Nutrition

Food provides valuable nutrients for cancer patients. Eating well during cancer treatment helps to speed recovery, ease side effects, and keep the treatment plan running smoothly.

Understanding Blood Cancers and Treatment Options

Leukemia, lymphoma, myeloma, myelodysplastic syndromes (MDSs) and myeloproliferative neoplasms (MPNs) are types of cancer that can affect the bone marrow, blood cells, lymph nodes and other parts of the lymphatic system. See the Disease Information pages to learn more about the different types of blood cancer.

Other Financial Assistance

LLS is part of the Cancer Financial Assistance Coalition (C-FAC), which helps cancer patients manage their financial challenges by:

Helping members communicate and collaborate
Educating patients and providers about resources and links to other organizations that provide information about C-FAC's resources
Advocating for cancer patients regarding the financial burdens of cancer care

Stefan

Not that long ago, leukemia was an invariably fatal disease. These cancers presented with such ferocity and aggression that in many cases patient decline was rapid, usually within weeks of initial diagnosis. This all changed in the 1940s when Dr. Sidney Farber pioneered the use of antimetabolite chemicals as a means of killing leukemia cells, the birth of the chemotherapy revolution.

Izabella

When I was twelve years old, I was diagnosed with a very rare type of leukemia found in children. I was life-flighted, had various treatments and procedures, and even had four blood transfusions. As incredibly shocking and terrifying as it all was, I pulled through in only a week of treatment. My type of leukemia is called chronic myeloid leukemia (CML). This leukemia is something that will be a part of me forever. Even still, I take a daily oral chemotherapy pill. Despite all of this, I maintain my path in life and will not let anything stop me.

Sherri

I lost my dad to leukemia 20 years ago, fundraising all year in his honor for the year he knew about his diagnosis but didn’t tell anyone. We also lost his mom (grandma) to leukemia in 2002 and my mother-in-law in 2007 to leukemia. I proudly support The Leukemia & Lymphoma Society (LLS) and try to donate every year, but this year, I hope to donate a big chunk to help current patients and their families.

Pam

Pam Katten died on September 24, 2002 after a year-long battle with acute myeloid leukemia (AML).

Matthew

Our Matthew was first diagnosed with acute lymphoblastic leukemia (ALL) in August 2015 at the age of 12. He relapsed with ALL in December 2016 and underwent his first bone marrow transplant in February 2017 with marrow from an anonymous male donor from New Jersey.

In January 2019, he was diagnosed with mixed phenotype acute leukemia (MPAL). He underwent his second bone marrow transplant in February 2019 with marrow from his first donor's twin brother. Our two families have become very close since we were able to meet after the first transplant.

Doug

In July 2014, my defibrillator fired while I was at a diner. Upon testing at the hospital I found out I have acute promyelocytic leukemia (APL). Much to my surprise, it was discovered by a simple blood test.

Mateo

Our Journey On June 26 2013, at six years old, Mateo was diagnosed with acute lymphoblastic leukemia (ALL). Our world was completely upside down since that night. Our hearts shattered when we processed the words "your child has cancer ".

Giulia Casorati, Ph.D.

A Leading Researcher Advancing Immunotherapy for Acute Myeloid Leukemia

In Italy, Dr. Giulia Casorati is focused on adoptive cell immunotherapy to treat patients with acute myeloid leukemia (AML). Immunotherapy is a groundbreaking approach to treatment that involves harnessing the power of the patient’s own immune system to kill cancer. She is developing an immunotherapy approach that engineers T cells to specifically target CD1, a molecule found on the surface of AML cells.

Monica

Our daughter, Monica, is a busy mother of three sweet girls, age 12 months, 3 years and 6 years. After a long winter filled with the girls’ colds, infections, and flu, Monica was exhausted.

Margot

I lost my father at age 53 to acute myeloid leukemia (AML) after a hard 13-month battle. I want to get involved with The Leukemia & Lymphoma Society (LLS) to spread awareness around leukemia and other blood cancers, to hopefully help other patients and loved ones going through this. My brother, Jack Austin, has run 2 marathons under the team "Running for Rob" and has fundraised over $10K for LLS. I want to get involved and fundraise to not only spread awareness and support to those dealing with this dreadful disease.

Graham

I am joining former England and Crystal Palace footballer and leukemia survivor, Geoff Thomas, and 23 other teammates to cycle the full Tour de France route one week ahead of the professionals to raise funds for the UK charity Cure Leukaemia. It's three huge goals — riding the Tour de France, raising $40,000 myself, and the team’s goal of $1 million. But with The Leukemia & Lymphoma Society’s (LLS) help, I know I can achieve it.

Tom

Hello Friends — this is my leukemia journey, For those of you who don’t know me, my entire 38-year teaching career was spent with 9-12 year olds. I’ve always relished the authenticity and passion of this age group and that led me to a very satisfying and rewarding chapter in my life.

Makenzie

My daughter Makenzie was diagnosed with chronic myeloid leukemia (CML) in January 2013, when she was just four years old. She had no signs or symptoms of leukemia. One day, Makenzie had a sore throat and we made an appointment with her pediatrician. Turns out she did have strep throat, but an exam also revealed her spleen was very enlarged. At that point, her pediatrician did bloodwork and learned that Makenzie's white cell count was through the roof. We were sent to Texas Children’s Hospital where later that evening she was diagnosed with CML.

Betty

In 2013, after doing the 60 mile, three day walk in support of breast cancer, of which I am also a survivor of, I realized that something seemed wrong as the walk was extremely difficult for me, unlike the previous 5 walks I had done. I made an appointment to see my doctor that next week and after doing some tests, I was told I had acute myloid leukemia. I was told I needed to check into the University of MN hospital that same day. And so began my journey with acute myeloid leukemia (AML).

Declaración de LLS sobre la estrategia federal de vacunación

Tina

My son Evan was diagnosed with acute lymphoblastic leukemia (ALL) when he was two years and seven months old. He went into remission a month later. He finished his chemotherapy and treatment, but shortly after he relapsed. He went through radiation and chemotherapy again and was given a bone marrow transplant. He never made it out of the hospital and passed away when he was four and a half. The reason I fundraise for The Leukemia & Lymphoma Society (LLS) is so other parents won’t have to go through what we went through.