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Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia
  • Is a cancer of the bone marrow and blood
  • Progresses rapidly without treatment
  • Does not have a clear cause

Click here to access ALL statistics. 

Click here to access information about ALL in children and teens. 

Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) 

Acute myeloid leukemia (AML) is a cancer of the bone marrow and the blood that progresses rapidly without treatment. AML mostly affects cells that aren’t fully developed, leaving these cells unable to carry out their normal functions. It can be a difficult disease to treat; researchers are studying new approaches to AML therapy in clinical trials.

Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL)
  • Is a type of blood cancer that begins in the bone marrow
  • Can progress either slowly or quickly depending on the form it takes

Click here to access CLL statistics.

Leukaemia Foundation of Australia

To fund research and to provide free services to support people with leukaemia, lymphoma, myeloma and related blood disorders, and their families in Australia.

  • Provides assistance over the phone, online and in person
  • Offers disease, treatment and clinical trial information
  • Helps with ground transportation, utilities and lodging
  • Provides support groups, peer matching and counseling
  • Funds research into the causes, epidemiology, diagnosis and treatment, psychosocial impact, management and cures of blood cancers and related disorders. 

Patients, caregivers, health professionals

Website or 1800 620 420 in Australia http://www.leukaemia.org.au/
International Resources
International Resources

Epigenetic Mechanisms in Acute Myeloid Leukemia

The goal of this project is to investigate the role of the epigenetic regulator Eleven-Nineteen-Leukemia (ENL) and its cancer mutations in acute myeloid leukemia (AML). Our studies leverage the expertise in chromatin biology, functional genomics, and AML modeling, as well as unique chemical compounds and mouse models. Results from this project will provide novel biological insights into our understanding of AML pathogenesis and facilitate the development of novel epigenetic therapies.

Large Granular Lymphocytic Leukemia

Large granular lymphocytic (LGL) leukemia is a type of chronic leukemia affecting white blood cells called "lymphocytes."  Lymphocytes are part of the body's immune system and help fight certain infections. LGL leukemia is characterized by enlarged lymphocytes, containing noticeable granules, which can be seen when the blood is examined under the microscope. There are two types of LGL leukemia: T-cell (T-LGL) and natural killer cell (NK-LGL). Each type may be chronic (slow-growing) or aggressive (fast-growing). 

Treatment of Acute Promyelocytic Leukemia

Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML). APL cells have a very specific abnormality that involves chromosomes 15 and 17, leading to the formation of an abnormal fusion gene called PML/RARα. This mutated gene causes many of the features of the disease. APL accounts for about 10-15 percent of all adult AML cases diagnosed each year. 

Curing AML in Elderly Patients

Robert Hromas, M.D., a blood cancer expert at the University of Florida's College of Medicine, is looking to discover new drugs that will improve the response of elderly AML patients to chemotherapy. His latest research, funded through a Translational Research Program grant from The Leukemia & Lymphoma Society, focuses on inhibiting the DNA repair response.

LGL Leukemia Registry at UVA

To learn more about this rare form of blood cancer and how to treat it.

  • Based at the University of Virginia Cancer Center in Charlottesville, under the direction of Thomas P. Loughran, Jr, MD
  • Participation in the registry is voluntary. Patients will be studied over time to learn more about the disease.
  • Patients will need to complete questionnaires and provide blood and tissue samples; these samples may be used to develop new tests or treatments.

Anyone diagnosed with Large Granulocytic Lymphocyte (LGL) Leukemia

Website https://uvahealth.com/services/lgl-leukemia-program

Hairy Cell Leukemia Foundation

To improve outcomes for patients by advancing research into the causes and treatment of hairy cell leukemia, as well as by providing educational resources and comfort to all those affected by hairy cell leukemia.

  • Provides information about hairy cell leukemia, referrals to health care centers and clinical trials
  • Organizes annual seminars bringing patients, clinicians and researchers together to learn from each other about the latest advancements in diagnosis and treatment
  • Offers an annual research grants program for medical professionals.

Patients, caregivers, health professionals, researchers

224-355-7201 https://www.hairycellleukemia.org
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