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Jazz Pharmaceuticals to Present New Data Highlighting Advancements in Rare Blood Cancers at ASH 2023

Celator

DUBLIN, Nov. 30, 2023 - Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that the Company and its partners will present six abstracts related to LLS TAP-supported Vyxeos (CPX-351) at the 65th Annual American Society of Hematology (ASH) Annual Meeting from December 9-12.

Vyxeos Presentations 

Presentation Title 

Author 

Presentation Details 

Population Pharmacokinetic-Pharmacodynamic Modeling of Neutrophil and Platelet Count for Lower-Intensity Therapy of CPX-351 Combined With Venetoclax in Acute Myeloid Leukemia  

Yali Liang, et al.  

Type: Poster 

Number: 2902 

Session: 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster II 

Date/Time: Sunday, December 10, 6:00-8:00 PM 

Abstract Link  

CPX-351 With Venetoclax in Patients with Relapsed/Refractory Acute Myeloid Leukemia: Results of a Phase Ib Study  

Alex Bataller, et al.  

Type: Poster

Number: 4259

Session: 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster III

Date/Time: Monday, December 11, 6:00-8:00 PM

Abstract link

Phase 2 Study of CPX-351 in Combination with Venetoclax in Patients with Newly Diagnosed, High Risk Acute Myeloid Leukemia  

Wei-Ying Jen, et al.  

Type: Poster

Number: 4273

Session: 615. Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster III

Date/Time: Monday, December 11, 6:00-8:00 PM

Abstract link

Results of a Phase 1/2 Study of Lower Dose CPX-351 for Patients with Int-2 or High Risk IPSS Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia after Failure to Hypomethylating Agents  

Guillermo Montalban-Bravo, et al.  

Type: Poster

Number: 1873

Session: 637. Myelodysplastic Syndromes Clinical and Epidemiological: Poster I

Date/Time: Saturday, Dec. 9, 5:30 PM-7:30 PM 

Abstract link  

CRISPR/Cas9 Screen Identifies CPX-351 and 7+3 Regimens Response Modulators with Distinct Sensitive and Resistant Profiles 

[IST] 

Nam Nguyen, et al.  

Type: Poster

Number: 1412

Session: 604. Molecular Pharmacology and Drug Resistance: Myeloid Neoplasms: Poster I

Date/Time: Saturday, Dec. 9, 5:30-7:30 PM

Abstract link

CPX-351 in Patients with Newly Diagnosed Post Myeloproliferative Neoplasms Acute Myeloid Leukemia

[IST]

Sylvain Garciaz, et al.

Type: Poster

Number: 2917

Session: 616. Acute Myeloid Leukemias: Investigational Therapies, Excluding Transplantation and Cellular Immunotherapies: Poster II

Date/Time: Sunday, Dec. 10, 6:00-8:00 PM

Abstract link

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