Polatuzumab vedotin-piiq
Details of the Drug
- Generic Name:
- Polatuzumab vedotin-piiq
- Drug Type:
- CD79b-directed antibody–drug conjugate
- How the Drug is Given:
Intravenous - Names:
- Polivy®
- Polatuzumab vedotin-piiq
Indications and Usage
Polatuzumab vedotin-piiq is FDA approved
- In combination with a rituximab product, cyclophosphamide, doxorubicin, and prednisone (R-CHP) for the treatment of adult patients who have previously untreated diffuse large B-cell lymphoma (DLBCL), not otherwise specified (NOS) or high-grade B-cell lymphoma (HGBL) and who have an International Prognostic Index score of 2 or greater.
- In combination with bendamustine and a rituximab product for the treatment of adult patients with relapsed or refractory DLBCL, NOS, after at least two prior therapies.
Side effects needing medical attention
The most common adverse reactions included neutropenia, thrombocytopenia, anemia, peripheral neuropathy, fatigue, diarrhea, fever, decreased appetite, and pneumonia.
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