Axatilimab-csfr
Details of the Drug
- Generic Name:
- Axatilimab-csfr
- Drug Type:
- Colony stimulating factor-1 receptor (CSF-1R)-blocking antibody
- How the Drug is Given:
Injection, for intravenous use
- Names:
- Axatilimab-csfr
- Niktimvo™
Indications and Usage
Axatilimab-csfr is indicated for the treatment of chronic graft-versus-host disease (cGVHD) after failure of at least two prior lines of systemic therapy in adult and pediatric patients weighing at least 40 kg (about 88 pounds).
Side effects needing medical attention
The most common adverse reactions, including laboratory abnormalities, are increased AST, infection (pathogen unspecified), increased ALT, decreased phosphate, decreased hemoglobin, viral infection, increased GGT, musculoskeletal pain, increased lipase, fatigue, increased amylase, increased calcium, increased CPK, increased ALP, nausea, headache, diarrhea, cough, bacterial infection, fever, and short of breath.
For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.