- Generic Name:
- Drug Type:
- Selective T cell co-stimulation modulator
- How the Drug is Given:
Injection, for intravenous use; Injection, for subcutaneous use
Indications and Usage
Abatacept is a indicated for the prophylaxis (prevention) of acute graft versus host disease (aGVHD), in combination with a calcineurin inhibitor and methotrexate, in adults and pediatric patients 2 years of age and older undergoing hematopoietic stem cell transplantation (HSCT) from a matched or 1 allele-mismatched unrelated donor.
Side effects needing medical attention
Most common adverse events are anemia, hypertension, CMV reactivation/CMV infection, fever, pneumonia, nose bleeds, CD4 lymphocytes decreased, hypermagnesemia, and acute kidney injury.