Dr. Yan Liu received his PhD degree in Molecular Biology from the Chinese Academy of Sciences. Yan completed his postdoctoral training in hematology in the laboratory of Dr. Stephen Nimer at the Memorial Sloan Kettering Cancer Center (MSKCC). Dr. Liu joined Indiana University School of Medicine as an Assistant Professor in 2010 and was promoted to Associate Professor in 2016. Currently, Dr. Liu is an Associate Professor at the Northwestern University Feinberg School of Medicine. Dr. Liu is the Co-leader of the Hematologic Malignancies Program at the Robert H. Lurie Comprehensive Cancer Center. The Liu laboratory investigates the molecular mechanisms underlying hematopoietic stem cell (HSC) aging and pathogenesis of clonal hematopoiesis of indeterminate potential (CHIP), myelodysplastic syndromes (MDS), and acute myeloid leukemia (AML). The goal of this Translational Research Program award is to understand the pathogenesis of MDS and develop novel therapeutic approaches to improve MDS treatment.