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BURLINGTON STORES RAISES RECORD-BREAKING $5.1 MILLION FOR LLS

Burlington Stores and The Leukemia & Lymphoma Society (LLS) joined forces for the 17th consecutive year to help save lives and bring smiles to those touched by blood cancer. From September 9 through December 1, Burlington’s more than 670 locations nationwide encouraged customers to donate $1 or more at checkout to support LLS’s goal to create a world without blood cancer. This campaign, combined with Burlington’s corporate associate fundraising efforts, raised a record smashing $5.1 million for LLS, helping the organization fund lifesaving research and treatments.

Enhancing efficacy of cyclin-dependent kinase inhibitors in diffuse large B-cell lymphoma

Nearly half of patients with diffuse large B-cell lymphoma (DLBCL), ultimately fail current therapies and die from their disease. Selective targeting of cyclin-dependent kinase 9 (CDK9) is a promising strategy, as evidenced by potent anti-tumor effects in preclinical models of DLBCL. Yet tumors evade therapy by developing resistance. This proposal seeks to both elucidate and circumvent the oncogenic events underlying this resistance in order to offer novel therapeutic approaches to treat DLBCL.

Companies Take on Blood Cancer

Corporations usually have enough on their plate, just taking care of business, but at least one has found a creative way to also help generate millions of dollars to fund blood cancer research, education and patient services.

Radiation Complete

Stronger Together: Navigating Cancer as Newlyweds

As we round out our first year of marriage and our first year of battling cancer, I recently asked my husband Brad how he would describe this past year. “Disrupted.” Before cancer, we had plans: big, extravagant, travel-the-world kind of plans. After two years of a long-distance relationship, we were finally going to live in the same city. We were going to get settled in our brand-new home. We were going to make new Florida friends. We were excited about the opportunities we had in our careers. We were going to capitalize on the “newlywed phase” to the fullest extent!

Random Acts of Light: Burlington and LLS Surprise Cancer Patient after Hurricane Harvey

Burlington Stores and The Leukemia & Lymphoma Society (LLS) surprised Mateo Rubio – a three-year-old boy with acute lymphoblastic leukemia (ALL), and his mother, Ana Torres – each with a gift card to Burlington, to help bring light to the darkness of cancer and to help purchase new belongings following the destruction of their home in Hurricane Harvey.

A College Freshmen Faces A Cancer Diagnosis

The symptoms I habitually pushed off as stressors from my first semester of college, began to accumulate. Throughout the semester I felt less like my healthy self because of coughing, abnormal skin reactions, unexplainable fatigue and diminishing motivation.

Advances in Cancer Research and Treatment in 2020

Progress in new cancer treatments is accelerating so rapidly that the standard of care for many cancer patients is changing right before our very eyes.

Since 2017, the U.S. Food and Drug Administration (FDA) has approved a remarkable 53 therapies just to treat patients with blood cancers, and The Leukemia & Lymphoma Society (LLS) has helped advance 46 of these treatments.

I have no reason to believe the next few years won’t be as productive and groundbreaking as the last few. With that, here are some of my predictions for 2020:

A Nurse’s Journey as a Blood Cancer Survivor

During National Nurses Week, observed each year from May 6 to May 12, we celebrate nurses across the country who are committed to our health and wellness. At The Leukemia & Lymphoma Society, we wanted to recognize Katie Demasi, a nurse and a blood cancer survivor, who has experienced both sides of the healthcare system. Here is her story…

Putting Patients at the Center of Care at #ASCO16

The American Society of Clinical Oncology (#ASCO16) annual meeting kicked off today as more than 30,000 researchers from around the world converged in Chicago to share their latest clinical findings on treatments and diagnostics for all cancers, and to exchange ideas about how to improve outcomes for cancer patients.

Can We Start Using The Word “Cure?” #ASH17

Today at the #ASH17 (American Society of Hematology) conference in Atlanta, researchers presented the latest compelling data from thousands of clinical trials, revealing how experimental therapies, or approved therapies being tested in new ways, have worked in treating blood cancer patients. Among the presentations were several hundred projects across a spectrum of diseases that benefited in some way from support from The Leukemia & Lymphoma Society (LLS).

“I Don’t Have Money but I Have Time”

Three or four days a week for the past five years, Dorothy Spriggs has been showing up for work at The Leukemia & Lymphoma Society’s (LLS) Maryland chapter. However, instead of a paycheck, she is earning the satisfaction of knowing she is doing her part to give back and helping others with blood cancer.

At age 73, the Baltimore woman known as “Ms. Dotti” has no plans to stop. She’s enjoying it way too much.

“It’s the joy of being able to give back in a small way,” she said. “When I look at what the staff do, it amazes me. What I do is kind of small compared to them.”

Progress and Challenges in Treating the Blood Cancers: #ASH19

It’s that time of year again, when more than 30,000 scientists specializing in blood cancers and other blood disorders, oncologists and hematologists, pharmaceutical and biotechnology company representatives, and cancer patient advocacy organizations gather in one place to learn about the latest progress in treatments and share new ideas.

This year, we’re in sunny Orlando for the 61st ASH (American Society of Hematology) Annual meeting and Exposition.

Cleaning Tips to Help Keep You and Your Loved Ones Safe

The Leukemia & Lymphoma Society (LLS) is here to help. We’ve put together guidance from the U.S. Centers for Disease Control and Prevention (CDC) and other tips to help caregivers and families keep their homes clean and healthy.

Racing Together to Find Blood Cancer Cures

The Leukemia & Lymphoma Society (LLS) Orange County Inland Empire Chapter is excited to announce a new partnership with Auto Club Speedway in Fontana, California. Auto Club Speedway, California’s premier motorsports facility, is geared up to support LLS by hosting a series of fundraising events throughout the coming year.

Auto Club Speedway continues to be involved in making a difference in the local community, and the driving force behind their partnership with LLS is the close connection blood cancer has had on the Speedway family.

Leveraging cancer registries, clinical trials, and community partnerships to address disparities in pediatric, adolescent, and young adult lymphoma

I aim to identify drivers of pediatric and adolescent/young adult lymphoma disparities so that targeted health equity interventions can be developed. Integration of large datasets, systematic collection of social determinants data in clinical trials, and collaboration with patient advocates will: a) create new population-based resources to study lymphoma outcomes; b) establish a novel framework for equity research in lymphoma clinical trials; and c) identify real-world targets for intervention.

Pluripotent Stem Cell-derived CAR-T and CAR-NK Cells for Immunotherapy of Leukemia and Lymphoma

Cytotoxic cells of the immune system, including T and NK cells, can be targeted to seek out and destroy leukemia, lymphoma and myeloma cells by engineering them to express chimeric antigen receptors (CARs) which empower the cell to home to and kill the cancer cells. Typically, such CAR-T and CAR-NK cells are generated from a patient's own blood, but sometimes heavy pre-treatment with chemotherapy leaves inadequate supplies of T and NK cells.