Venetoclax

Details of the Drug

Generic Name:: Venetoclax
Drug Type:: BCL-2 inhibitor
How the Drug is Given:: By Mouth
Names:: Venclexta®; Venetoclax

Indications and Usage

Venetoclax is FDA approved

For the treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
In combination with azacitidine, or decitabine, or low-dose cytarabine for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adults who are age 75 years or older, or who have comorbidities that preclude use of intensive induction chemotherapy.

Side effects needing medical attention

Neutropenia, diarrhea, nausea, anemia, upper respiratory tract infection, thrombocytopenia, and fatigue. Serious adverse reactions were pneumonia, febrile neutropenia, pyrexia (fever), autoimmune hemolytic anemia, anemia, and tumor lysis syndrome (TLS).

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