Inotuzumab Ozogamicin

Details of the Drug

Generic Name:: Inotuzumab ozogamicin
Pronunciation:: ih-noh-TOO-zoo-mab OH-zoh-ga-MIH-sin
Drug Type:: Antibody conjugate
How the Drug is Given:: Intravenously (IV)
Names:: Besponsa®; Inotuzumab Ozogamicin

Indications and Usage

Inotuzumab ozogamicin is FDA approved for the treatment of relapsed or refractory CD22-positive B-cell precursor acute lymphoblastic leukemia (ALL) in adult and pediatric patients 1 year and older.

Side effects needing medical attention

Thrombocytopenia (low platelets), neutropenia (low neutrophils), infection, anemia, leukopenia (low white blood cells), fatigue, hemorrhage, pyrexia (fever), nausea, headache, febrile neutropenia, transaminases increased, abdominal pain, gamma-glutamyl transferase increased, and hyperbilirubinemia (increased bilirubin).

WARNING: Hepatotoxicity, including hepatic venoocclusive disease (VOD) (also known as sinusoidal obstruction syndrome) and increased risk of post-hematopoietic stem cell transplant non-relapse mortality. See full prescribing information for complete boxed warning.

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.