ImCheck Presents Initial Patient Data from the EVICTION-2 Clinical Trial at SITC Annual Meeting
Current TAP Partner
Marseille, France, November 11, 2022 – ImCheck Therapeutics presented today the first patient data from EVICTION-2, a Phase I/II clinical trial evaluating the combination of ImCheck’s lead program, ICT01, a γ9δ2 T cell-activating monoclonal antibody targeting BTN3A, combined with low-dose (LD) IL-2, to selectively expand the number of γ9δ2 T cells in relapsed/refractory patients with solid tumors. In a poster presentation at the Society for Immunotherapy of Cancer (SITC) 37th Annual Meeting being held in Boston, ImCheck researchers and academic collaborators showed data of the combination’s ability to safely and reproducibly induce γ9δ2 T cell activation, expansion, and migration out of the circulation, which was accompanied by similar effects on CD8 T cells and Natural Killer cells (NKs).